Tottenham Hotspur vs Atletico Madrid Predictions, Betting Tips and Odds

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Wednesday, 18 Mar.
22:00 GMT+3

Tottenham Hotspur host Atletico Madrid at Tottenham Hotspur Stadium on 18 March at 22:00 (GMT+3) in the Champions League knockout stage.

Atletico Madrid’s 5-2 first-leg win leaves Tottenham needing a major turnaround, while the Spanish side should be able to complete the job and progress.

Below is the full match preview, predictions and betting analysis.

Tottenham vs Atletico Madrid Tips

  • Tottenham vs Atletico Madrid: Atletico Madrid to Win @ with N/A
  • Tottenham vs Atletico Madrid: Julian Alvarez to Score Anytime @ with N/A

*Odds correct at the time of publication and subject to change.

Tottenham vs Atletico Madrid Odds

Result Odds
Tottenham
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Draw
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Atletico Madrid
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*Odds correct at the time of publication and subject to change.

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Tottenham vs Atletico Madrid Prediction

Atletico’s first-leg control sets the direction

Atletico Madrid carry a 5-2 advantage from the first leg in Spain, a result that frames the second leg as a game Tottenham must chase from the outset. Spurs remain winless in eight matches across all competitions, with six defeats in that run, and the sequence continues under Igor Tudor.

That stretch includes the immediate aftermath of the Madrid defeat, where Tottenham earned a point at Anfield against Liverpool despite the pressure around results. It adds a layer of resistance, though the wider run still points to a side struggling to convert performances into wins.

Atletico arrive with six wins from their last seven games and a current three-match winning streak, a consistent return that aligns with the first-leg margin. While they have only one win in five away Champions League matches this season, the aggregate score reduces the need for risk and keeps the tie within their control.

Tottenham’s squad issues add to that picture. Cristian Romero and Joao Palhinha are unavailable, while Richarlison is suspended, extending an already lengthy injury list. With a crucial Premier League fixture against Nottingham Forest ahead, priorities may begin to split.

A 5-2 aggregate lead, combined with Tottenham’s eight-game winless run and six defeats in that spell, leaves the visitors in a position where another win looks well within reach at 2.45 and makes plenty of appeal.

Tip: Atletico Madrid to Win @ with N/A

Alvarez’s European scoring rhythm holds firm

Julian Alvarez has scored seven goals in 10 Champions League appearances this season, a steady return that includes two goals in the first leg against Tottenham. His output in this competition remains consistent across the campaign.

He featured for only 25 minutes in the 1-0 win over Getafe at the weekend, which keeps his workload relatively light ahead of this trip. That limited involvement suggests fresh legs for a player already delivering regularly in Europe.

The first-leg brace highlights his role in key moments, and that contribution sits within Atletico’s broader run of six wins in seven matches. Tottenham’s defensive absences, including Romero, sit in the background here as a structural limitation rather than a direct scenario driver.

Seven goals in 10 games, alongside two in the previous meeting, keep his scoring frequency clear within this tournament run. Alvarez to score anytime at 2.50 is hard to ignore.

Tip: Julian Alvarez to Score Anytime @ with N/A

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